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Bii International Consortium Members

Core Working Group

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Prof. dr. Prabath Nanayakkara, MD, PhD, FRCP

Amsterdam UMC~ Professor in Acute Internal Medicine
Head, Section General Internal Medicine

​Biography:

​Prof. Dr. Prabath W. B. Nanayakkara, is a Sri Lankan born (acute) physician and professor of acute internal medicine, director, acute medicine residency programme, Head, acute medical unit, Amsterdam UMC location VU University Medical Center. Certified general internal, vascular, acute, medicine consultant. President, section acute medicine, Dutch association of Internal Medicine.​
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KEY PUBLICATIONS:

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Jan Willem Cohen Tervaert MD, PhD

Canada~ Rheumatologist - Clinical Immunologist
Netherlands~ Internist - Immunologist

​Biography:

Jan Willem Cohen Tervaert MD, PhD

Cohen Tervaert studied Medicine at the University of Groningen, the Netherlands, where he obtained his MD in 1981. After training in Internal Medicine and Nephrology, he finished his thesis cum laude in 1990 entitled "ANCA: new class of autoantibodies in glomerulonephritis and vasculitis".

Subsequently, he worked as a visiting researcher in the Vascular Biology Department, Harvard Medical School Boston, USA (Head: Prof. MA Gimbrone Jr.).

In 1993, he returned to Groningen (as a recipient of a fellowship of the Royal Netherlands Academy of Arts and Sciences), where he was a staff member at the Division of Clinical Immunology, Department of Medicine, at the University Medical Center Groningen.

In 2000, he was appointed Professor of Medicine and Immunology at the Maastricht University, Maastricht, the Netherlands.

From 2002 -2006, he was a member of the WHO committee assessing autoimmunity associated with exposure to chemicals.

In 2020, he was appointed as a member of the European Commission expert panel on medical devices.

 

Furthermore, he was until 2012 chairman of the Division of Clinical and Experimental Immunology of the Department of Internal Medicine and head of the Immunology Laboratory at the Maastricht University Medical Center.

From 2012 -2015, he was Research Director of the Sint Franciscus Vlietland Group in Rotterdam, the Netherlands (one of the largest “top-clinical hospitals” of the country).

Currently, he is a Professor at the University of Alberta, Edmonton, Canada, where he is since November 1st, 2017 the Director of the Division of Rheumatology.

Cohen Tervaert is a founding member of the Autoimmunity Consortium, of the North American Vascular Biology Organization and of the Dutch Vasculitis Study Group.

He is a former Chairman of the scientific advisory board of the Dutch Arthritis Foundation (“Reumafonds”), a former chairman of the Dutch Scientific Section of Nephrology and a former board member of the Dutch Federation of Nephrology and the Dutch Society of Immunology.

He was (until recently) a member of the scientific advisory board of The National Health Care Institute that advises the Dutch Minister of Health, Welfare, and Sports on health care coverage and medications in the Netherlands, a member of the Netherlands National Institute for Public Health and the Environment committee on Chromium-VI and a member of the Health Council of the Netherlands committee on ME/CFS.

His fields of interest are inflammation and autoimmunity of vascular disorders, such as atherosclerosis and vasculitis. Genes and the interplay with environmental factors such as vitamin D, S. aureus, silica, and foreign body implantation such as silicones and polypropylene mesh in the development of autoimmunity have his special interest. Recently, he started together with Dr. Mo Osman a laboratory in which the role of mitochondrial dysfunction in relation to fatigue and NK cells is investigated in diseases such as vasculitis, systemic sclerosis, ASIA, fibromyalgia and COVID-19.

He is (co) author of more than 440 scientific articles that are cited in over > 29.600 publications. He is a member of Editorial Boards of 3 scientific journals. His Hirsch factor per 01-07-2020 is 87.

 

KEY PUBLICATIONS:

1. Cohen Tervaert JW, van der Woude FJ, Fauci AS, Ambrus JL, Velosa J, Keane WF, Meijer S, van der Giessen M, The TH, van der Hem GK, Kallenberg CGM. Association between active Wegener's Granulomatosis and anticytoplasmic antibodies. Arch Int Med, 1989;149:2461-2465.

 2. Cohen Tervaert JW, Huitema MG, Hene RJ, et al. Prevention of relapses of Wegener’s Granulomatosis by treatment based on antineutrophil cytoplasmic antibody titre. Lancet 1990; 336:709-711.

 3. Stegeman CA, Cohen Tervaert JW, De Jong PE, et al. Trimethoprimsulfamethoxazole (Co-trimoxazole) for the prevention of relapses of Wegener’s granulomatosis. N Engl J Med 1996; 335:16-20.

4. Jayne D, Rasmussen N, Andrassy K, Bacon P, Cohen Tervaert JW, et al. A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N Engl J Med 2003; 349:36-44.

5. Jones RB, Cohen Tervaert JW, Hauser T et al. Rituximab versus cyclophosphamide in ANCA associated renal vasculitis. New Engl J Med 2010;363:211-220

 6. Wilde B, Van Paassen P, Witzke O, Cohen Tervaert JW. New pathophysiological insights and treatment of ANCA-associated vasculitis. Kidney Int 2011;79:599-612

7. Lyons PA, Rayner TF, Trivedi S, Holle JU, Watts RA, Jayne DR, Baslund B, Brenchley P, Bruchfeld A, Chaudhry AN, Cohen Tervaert JW, et al. Genetically distinct subsets within ANCA-associated vasculitis. N Engl J Med. 2012 Jul 19;367(3):214-23.

8. Bossuyt X, Cohen Tervaert JW, Arimura Y, et al. Revised 2017 International Consensus on testing of ANCA in small vessel vasculitis. Nature Rev Rheumatol 2017 Nov;13(11):683-692.

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9. Moiseev S, Bossuyt X, Arimura Y, Blockmans D, Csernok E, Damoiseaux J, Emmi G, Flores-Suárez LF, Hellmich B, Jayne D, Jennette JC, Little MA, Mohammad AJ, Moosig F, Novikov P, Pagnoux C, Radice A, Sada KE, Segelmark M, Shoenfeld Y, Sinico RA, Specks U, Terrier B, Tzioufas AG, Vaglio A, Zhao MH, Cohen Tervaert JW; European EGPA Study Group. International Consensus on ANCA Testing in Eosinophilic Granulomatosis with Polyangiitis. Am J Respir Crit Care Med. 2020 Jun 25. doi: 10.1164/rccm.202005-1628SO. 

 

10. Osman MS, van Eeden C, Cohen Tervaert JW. Fatal COVID-19 infections: Is NK cell dysfunction a link with autoimmune HLH? Autoimmun Rev. 2020 Jul;19(7):102561. doi: 10.1016/j.autrev.2020.102561

10.1016/j.autrev.2020.102561

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Lu-Jean Feng, MD

Ohio~ Medical Director, Founder, Board-Certified Plastic and Reconstructive Surgeon, Feng Clinic

Biography: Dr. Lu-Jean Feng is an internationally renowned Microvascular Plastic and Reconstructive Surgeon. She is the Founder and Medical Director of The Lu-Jean Feng Clinic. Dr. Feng graduated from Yale College and Yale Medical School and has been involved in medicine for more than 28 years. She is unique within her field, as female plastic surgeons comprise a very small percentage of the total industry due to the intensity and length of training required. Dr. Feng is widely recognized as an artist, surgeon and visionary for her many endeavors in the medical field and for her ability to help patients improve and maximize their overall health and well-being when all other avenues have failed. To date, Dr. Feng has patients from every state in the U.S. and from over 36 countries around the world. Over the years, Dr. Feng’s own personal beliefs and ideals regarding fitness, nutrition, and healthy living have evolved into every aspect of her practice. The Lu-Jean Feng Clinic opened in 1999, as a premier state-of-the-art outpatient surgery center. Today, the 15,000 square foot, 3-story building has been transformed into a total health and wellness center, incorporating many beneficial services under one roof; preventive medicine, medical-grade skin care services, laser treatments, infrared sauna, cryotherapy, ionic foot detoxification, hyperbaric oxygen, massage therapy, FengFit™ Cafe and Feng Fitness center. In 2011 Dr. Feng developed a line of healthy plant-based foods under the name, FengFit™ Plant-Based Cuisine. All surgery patients receive a quart of Dr. Feng’s highly nutritious fresh soup of the day along with Dr. Feng’s Signature Salad upon discharge from the facility. Dr. Feng has very high ethical standards and is a masterful technical surgeon who pays close attention to the most minute details and takes great pride in her work. Her latest pursuit involves helping her patients reach total health and wellness through her highly specialized Nutrigenomic testing and Bio-Identical Hormone Replacement Therapy program. Dr. Feng’s ultimate goal is to guide each and every patient to a more optimal state of health through proper nutrition, rigorous exercise, vitamins and supplements and replacement of essential bioidentical hormones. In other words, total and optimal wellness from the inside out to ensure vitality, slow the aging process, and provide protection from disease.

PROFILE OF LU-JEAN FENG, M.D. www.drfeng.comwww.fengclinic.comSpecialty: • Cosmetic Surgery of the Face and Breast • Natural Breast Enhancement with Fat, Stem Cells and PRP • Painless/Drainless Abdominoplasty (Tummy Tuck) • Advanced Bio-Identical Hormone Replacement Therapy (BHRT) • Nutrigenomic Testing and Analysis Affiliations: • Board Certified by The American Board of Plastic Surgery • Privileges at University Hospitals Ahuja Medical Center • Certified in Advanced Bio-Identical Hormone Replacement Therapy • Founder and Medical Director of The Lu-Jean Feng Clinic • Member of The American Society of Plastic Surgeons (ASPS) • Member of American Society of Reconstructive Microsurgery • Member of the International Visiting Committee at Case Western Reserve University • Member of the Age Management Medicine Group (AMMG) • Member of The Academy of Preventive & Integrative Medicine • Member of The American Academy of Anti-Aging Medicine Education: • Yale College - Bachelor of Science in Molecular Biophysics and Biochemistry • Yale Medical School - Doctor of Medicine • University of California at San Francisco (UCSF) -Residency in General Surgery • University of North Carolina at Chapel Hill (UNC) - Residency in Plastic Surgery • New York University (NYU) - Fellowship in Microvascular Surgery Major Accomplishments: • Attended Yale College at the Age of Sixteen • Internationally Renowned for Specialized Technical Skills in Microvascular Breast Reconstruction Using Autogenous Tissue • Former Head of Microvascular Plastic Surgery at Mt. Sinai Medical Center of Cleveland 1989 - 1999 • First Physician in Northeast Ohio to Successfully Transfer Tissue from the Buttock to Breast Following Mastectomy • Co-Investigator in the National Institute of Health Grant to Study the Immunology of Silicone • Television appearances on Dateline NBC, Good Morning America, Extra, Live on Five, Fox TV-8, WKYC TV-3, The Morning Exchange, MTV True Life, Real Housewives of Beverly Hills • Featured and Written About by The Associated Press, Wall Street Journal, Cleveland Plain Dealer, Cleveland Magazine, New Cleveland Woman, New Woman, Ms., and Shape • Featured and Written About in the following Books; Informed Consent by John Byrne and The Silicone Breast Implant Controversy by Dr. Frank B. Vasey • Seven Year Study and Research Paper, Analysis of Risk Factors Associated with Rupture of Silicone Breast Implants published in Plastic and Reconstructive Surgery, September 1999, Vol. 104, No 4 • Pathology of Lymph Nodes From Patients With Breast Implants A Histologic and Spectroscopic Evaluation, published in Am J Surg. Path Volume 29, Number 4, April 2005 • Ellis Island Medal of Honor - New York City, May 2006 • Rainmaker Award - Healthcare, Cleveland, Sept. 2007 • Ten Year Study and Research Paper, Painless Abdominoplasty: The Efficacy of Combined Intercostal and Pararectus Blocks in Reducing Post-Operative Pain and Recovery Time, Plastic and Reconstructive Surgery, November 2010, Vol. 126, No. 5 • Developed a proprietary line of healthy foods under the name of FengFit™ Plant-Based Cuisine. • Understanding Breast Implant Illness Before and After Explantation: A Patient Reported Outcomes Study, published in Annals of Plastic Surgery, Volume 85, July 2020. • Invited Guest Speaker at the American Society for Aesthetic Plastic Surgery - Las Vegas - April 2020 - Topic: Breast Implant Illness • Improvement of Pulmonary Function After Removal of Breast Implants and Total Capsulectomy: An Objective Outcome Assessment in Breast Implant Illness, To be presented at the Plastic Surgery Research Council, Montreal, Canada, May 2020 Personal Data: • Born in Taipei, Taiwan and moved to the United States at age 12 • Enjoys exercising, traveling, playing tennis and reading • Avid fitness and nutrition enthusiast and NBA fan

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